DHEA (dehydroepiandosterone) DHEA (dehydroepiandrosterone) is produced by the adrenal glands, which sit atop the kidneys. It is the precursor to the estrogen and testosterone and cortisol pathway. Much like human growth hormone (HGH) and melatonin two other hormones now known to have anti-aging properties DHEA is produced in abundance during youth, peaking around the age of 20-25. Over stimulation of the adrenals from past abuse (dieting, stimulants, high stress levels, etc.) can exhaust the adrenal synthesis of DHEA.
Research has shown that DHEA has many functions in the body pertaining to health and longevity. Among other things, it helps to generate the sex hormones estrogen and testosterone; increases the percentage of muscle mass; decreases the percentage of body fat; and stimulates bone deposition, thereby helping to prevent osteoporosis.
PREGNENALONE ( Master Hormone ) Pregnenolone is the ultimate parent steroid compound. All steroid hormones in the body (including cortisone, testosterone, estrogen, progesterone, DHEA and others) are produced from pregnenolone, which in turn is synthesized from cholesterol.
Progesterone and DHEA are also parent steroids in the sense that they can give rise to a number of other steroid species, but only pregnenolone is the ultimate precursor of all other steroid hormones. Levels of endogenous (made in the body) pregnenolone decline with age, as do levels of DHEA. However, normal levels of pregnenolone at various ages for each gender in humans have not been as clearly established as with DHEA.
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